Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: LP3K]
CAT#: TA353302L
Mouse monoclonal Anti-Keratin8 Clone LP3K
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Specifications
Product Data | |
Clone Name | LP3K |
Recommended Dilution | IHC ; IF ; WB |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes. |
Formulation | PBS with 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Purified by affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 52 |
Gene Name | keratin 8 |
Database Link | |
Background | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. Keratin 8 is the tissue polypeptide antigen (TPA) reported to be present in the serum of cancer patients. |
Synonyms | CARD2; CK-8; CK8; CYK8; K2C8; K8; KO |
Reference Data | |
Protein Families | Druggable Genome |
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