MMP1 Mouse Monoclonal Antibody [Clone ID: 3B6]

CAT#: TA353335L

Mouse monoclonal Anti-MMP1 Clone 3B6

Product Images

400 ng samples of recombinant human pro-enzyme (lane 1 = MMP-1; lane 2 = MMP-3; lane 3 = MMP-2; lane 4 = MMP-9) were subjected to SDS-PAGE, transferred to PVDF membrane and detected by immunoblotting with Mab 3B6 specific for MMP-1.

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  IHC staining of human colon carcinoma.

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  Tissues tested for MMP-1 expresstion using Mab 3B6.

Specifications

Product Data

• Clone Name: 3B6
• Applications: IHC, WB
• Recommended Dilution: IHC ; IF ; IP ; WB
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide; CSSFGFPRTVKH
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 1
• Database Link:
  NP_002412
  Entrez Gene 4312 Human
  UniProt ID P03956
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
• Synonyms: CLG; CLGN
• Note: (i) no cross-reactivity in immunoblot panel (MMP-2, -3, -9); (ii) staining in antigen-positive wax-imbedded tissues

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Bladder cancer, Pathways in cancer, PPAR signaling pathway