MMP9 Mouse Monoclonal Antibody [Clone ID: 4A3]

CAT#: TA353339L

Mouse monoclonal Anti-a-MMP9 Clone 4A3

Product Images

Western Bolt application of mAb 4A3

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  Immunohistochemical localisation of activated MMP-9 in oesophageal cancer using mAb 4A3

Specifications

Product Data

• Clone Name: 4A3
• Applications: IHC, WB
• Recommended Dilution: ELISA ; IHC ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide; acetylated-FQTFEGDLK
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 9
• Database Link:
  NP_004985
  Entrez Gene 4318 Human
  UniProt ID P14780
• Background: Matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal physiological processes as well as in disease processes. Tissue inhibitors of metalloproteinases (TIMPs) are the main physiological regulators of the MMPs. The TIMPs are secreted proteins that complex with individual MMPs and regulate the activity of specific MMPs. Together, the MMPs and TIMPs form a complex biological system strictly controlling degradation of ECM. The MMPs and TIMPs have a significant role in facilitating tumour invasion and metastasis
• Synonyms: CLG4B; GELB; MANDP2; MMP-9
• Note: Western Blot: not reactive with proenzyme of MMP-9, nor proenzyme or activated forms of MMP-2

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Bladder cancer, Leukocyte transendothelial migration, Pathways in cancer