CD31 (PECAM1) Mouse Monoclonal Antibody [Clone ID: JC70]

CAT#: TA353379L

Mouse monoclonal Anti-PECAM1 Clone JC70

Specifications

Product Data

• Clone Name: JC70
• Recommended Dilution: FACS ; IHC ; IF ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Cell membrane preparation from the spleen of a patient with hairy cell leukaemia
• Formulation: PBS with 0.02% Sodium Azide
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: platelet and endothelial cell adhesion molecule 1
• Database Link:
  NP_000433
  Entrez Gene 5175 Human
  UniProt ID P16284
• Background: PECAM1 (CD31) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, particular T-cell subsets, and is also a major constituent of the endothelial cell intercellular junction. PECAM1 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. JC70 is a good marker of endothelial cells in paraffin sections.
• Synonyms: CD31; EndoCAM; endoCAM; GPIIA; PECA1; PECAM-1
• Note: Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration