ASPP1 (PPP1R13B) Sheep Polyclonal Antibody

CAT#: TA353396L

Sheep polyclonal anti-ASPP1 antibody

Specifications

Product Data

• Recommended Dilution: IF ; IP ; WB
• Reactivities: Human
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ASPP1
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein phosphatase 1 regulatory subunit 13B
• Database Link:
  NP_056131
  Entrez Gene 23368 Human
  UniProt ID Q96KQ4
• Background: Stimulating protein of p53 (ASPP) contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. There are three known types of ASPP: ASPP1, ASPP2 and iASPP1. iASPP1 inhibits the proaptotic functions of ASPP1 and p53.
• Synonyms: ASPP1; p53BP2-like; p85

Reference Data

• Protein Families: Druggable Genome