CD45 (PTPRC) Mouse Monoclonal Antibody [Clone ID: C11]

CAT#: TA353403L

Mouse monoclonal Anti-PTPRC Clone C11

Specifications

Product Data

• Clone Name: C11
• Recommended Dilution: IHC ; IP
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human lymphocytes
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 180-222
• Gene Name: protein tyrosine phosphatase, receptor type C
• Database Link:
  NP_002829
  Entrez Gene 5788 Human
  UniProt ID P08575
• Background: PTPRC is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). C11 may be used for differential diagnosis of lymphoma and carcinoma and identification of haemopoietic tumours.
• Synonyms: B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway