WIPI2 Mouse Monoclonal Antibody [Clone ID: 2A2]

CAT#: TA353546L

Mouse monoclonal Anti-WIPI2 Clone 2A2

Specifications

Product Data

• Clone Name: 2A2
• Recommended Dilution: IF ; IP ; WB
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Synthetic peptide corresponding to C-terminus of WIPI2b CSALRLDEDSEHPPMILRTD
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 49 kDa
• Gene Name: WD repeat domain, phosphoinositide interacting 2
• Database Link:
  NP_056425
  Entrez Gene 74781 MouseEntrez Gene 26100 Human
  UniProt ID Q9Y4P8
• Background: This antibody is useful for the detection of WIPI-2, an essential protein for autophagy. WIPI2 is a mammalian effector of PtdIns3P and is ubiquitously expressed in a variety of cell lines. WIPI2 is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. WIPI-2 is the mammalian homologue of Atg18.
• Synonyms: ATG18B; Atg21; CGI-50; WIPI-2
• Note: Autophagosomes only detectable after induction of autophagy.