Dystrophin (DMD) Mouse Monoclonal Antibody [Clone ID: SPM 499]

CAT#: TA353791

Mouse Monoclonal anti-Dystrophin Antibody

Product Images

Human Skeletal Muscle stained with anti-Dystrophin antibody.

Specifications

Product Data

• Clone Name: SPM 499
• Applications: IHC
• Recommended Dilution: IHC-P
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Synthetic peptide corresponding to C-terminus of human dystrophin.
• Formulation: PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
• Purification: protein A/G
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 427 kDa
• Gene Name: dystrophin
• Database Link:
  NP_004006
  Entrez Gene 1756 Human
• Background: Dystrophin is a member of the spectrin/alpha-actinin family of actin-binding, triple helix rodcontaining proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchennes muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation. This antibody is highly specific to dystrophin and shows no cross-reaction with C-protein (an isoform of β-actinin), β-actin, or human muscle spectrin.
• Synonyms: BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85

Reference Data

• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis