MMP3 Rabbit Polyclonal Antibody

CAT#: TA354167

Rabbit anti MMP-3 (MMP-10) Polyclonal Antibody

Specifications

Product Data

• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein encoding human MMP-3 aa 251-478.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa/59 kDa
• Gene Name: matrix metallopeptidase 3
• Database Link:
  NP_002413
  Entrez Gene 4314 Human
  UniProt ID P08254
• Background: Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) is implicated in the invasive potential of malignant tumors. Stromelysin (MMP3 / Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens.
• Synonyms: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1

Reference Data

• Protein Families: Druggable Genome, Protease