Insulin (INS) Mouse Monoclonal Antibody

CAT#: TA354198

Mouse anti Insulin Monoclonal Antibody


USD 300.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications IHC
Recommended Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivities Human, Rat, Pig
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant full length of human Insulin Protein.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size ~6 kDa
Gene Name insulin
Background Insulin is a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as β-cell of islets of Langerhans and tumor (insulinoma) marker.
Synonyms IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Insulin signaling pathway, Maturity onset diabetes of the young, mTOR signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Regulation of autophagy, Type I diabetes mellitus, Type II diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.