Metabotropic Glutamate Receptor 5 Rabbit Polyclonal Antibody

CAT#: TA354236

Rabbit anti mGluR5 Polyclonal Antibody


USD 355.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC
Recommended Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivities Human, Rabbit, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide derived from C-terminus of human Glutamate receptor. This sequence is identical to human and rat.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 130 kDa
Background Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2) which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
Synonyms GPRC1E; mGlu5; MGLUR5; PPP1R86
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Gap junction, Huntington's disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.