Ubiquitin (UBB) Rabbit Polyclonal Antibody

CAT#: TA354260

Rabbit anti Ubiquitin Polyclonal Antibody

Product Images

IHC: Human Alzheimer brain stained with Anti-ubiquitin antibody, at 1:100 for 10 min at RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to C-term of ubiquitin protein.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ubiquitin B
• Database Link:
  NP_001268645
  Entrez Gene 7314 Human
  UniProt ID P0CG47
• Background: Ubiquitin (Ub) is a highly conserved protein of approximately 8.5 kDa. It plays a very important role in regulated non-lysosomal ATP dependent protein degradation. The protein to be degraded is covalently attached to C-term of ubiquitin, and the ubiquinated protein is then selectively degraded by a 26S complex, multicatalytic cytosolic and nuclear protease termed proteasome. The Ub-proteasome proteolytic pathway, which is a complex process, is implicated to be of great importance for regulating numerous cellular processes.
• Synonyms: FLJ25987; MGC8385; OTTHUMP00000064960; OTTHUMP00000064961; UBA80; UBCEP1; UBCEP2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Parkinson's disease