c Fos (FOS) Rabbit Polyclonal Antibody
Other products for "FOS"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to N-term of c-Fos protein. This sequence is identical in human, mouse, rat abd bovine. |
Formulation | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
Purification | The Rabbit IgG is purified by Epitope Affinity Purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | ~55 kDa |
Gene Name | Fos proto-oncogene, AP-1 transcription factor subunit |
Database Link | |
Background | The c-Fos proto-oncogene, an 55 kDa nuclear phosphor-protein, belongs to a family of transcription factors. It plays important roles in cell proliferation and differentiation. c-Fos is associated with the c-Jun protein, forming a stable c-Fos/c-Jun heterodimeric complex, this complex binds to the DNA promoter region which regulate transcription. Expression of the c-Fos gene is low in most normal adult tissues. However, high levels of expression have been detected in normal skin. |
Synonyms | AP-1; C-FOS; p55 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway |
Documents
Product Manuals |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.