Insulin Receptor (INSR) Mouse Monoclonal Antibody

CAT#: TA354344

Mouse anti Insulin Receptor (IR) Monoclonal Antibody

Product Images

WB: The cell lysate derived from Human IM-9 lymphocytes (5 mg/ml) was immunoprecipitated by Mouse anti-IR-1 at 10 ug/ml. A major band around ~135 kDa is observed.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Highly purified human placental Insulin Receptor.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: ~135 kDa
• Gene Name: insulin receptor
• Database Link:
  NP_000199
  Entrez Gene 3643 Human
  UniProt ID P06213
• Background: The human insulin receptor is a heterotetrametric membrane glycoprotein consisting of disulfide-linked subunits in a β-a-a-β Configuration. The beta-subunit (95kDa) possesses a single transmembrane domain, whereas the alpha subunit (135kDa) is completely extracellular.
• Synonyms: CD220; HHF5

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Adherens junction, Insulin signaling pathway, Type II diabetes mellitus