ICAM1 Rabbit Polyclonal Antibody

CAT#: TA354412

Rabbit anti CD54 Polyclonal Antibody

Product Images

WB: The cell lysate derived from Raji was immunoblotted by the Rabbit anti-CD72 antibody at 1:500. An immunoreactive bands was observed around 45kDa.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein encoding aa 253-367 of human CD54.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 85~110 kDa
• Gene Name: intercellular adhesion molecule 1
• Database Link:
  NP_000192
  Entrez Gene 3383 Human
  UniProt ID P05362
• Background: The CD54 antigen (ICAM-1) is an integral membrane glycoprotein of 85-110kDa with seven potential N-linked glycosylation sites. The cell surface glycoprotein is typically expressed on endothelial cells and the cells of the immune system, such as monocytes. It binds to integrins of type CD11a/CD18, or CD11b/CD18. Expression of the CD54 glycoprotein can be induced or upregulated on many cells types including B and T lymphocytes, thymocytes, fibroblasts, keratinocytes and epithelial cells. The CD54 antigen is important in mediating immune and inflammatory responses.
• Synonyms: BB2; CD54; P3.58

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Viral myocarditis