ADAM10 Rabbit Polyclonal Antibody

CAT#: TA354435

Rabbit anti ADAM10/KUZ Polyclonal Antibody

Product Images

WB: The Cell lysate derived from human leukemia cells Reh was immunoprobed by Rabbit anti-ADAM10 antibody at 1:500. An immunoreactive band is observed around ~.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to the C-terminus of ADAM10 protein from human, mouse and rat origins.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: ADAM metallopeptidase domain 10
• Database Link:
  NP_001101
  Entrez Gene 102 Human
  UniProt ID O14672
• Background: ADAM10 is a member of the ADAM (A Disintegrin And Metalloprotease) family of membrane-anchored glycoproteins comprised of several distinct protein modules, including a pro- and metalloprotease domain, disintegrin domain, cysteine-rich region and an EGF repeat. These proteases perform essential functions in cell adhesion and fusion in diverse systems and participate in ectodomain shedding of molecules such as TNF-a and Drosophila signaling molecule Notch.
• Synonyms: AD10; AD18; CD156c; HsT18717; kuz; MADM; RAK

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane
• Protein Pathways: Alzheimer's disease, Epithelial cell signaling in Helicobacter pylori infection