ORP150 (HYOU1) Rabbit Polyclonal Antibody

CAT#: TA354517

Rabbit anti HYOU1 Polyclonal Antibody

Product Images

WB: Tissue lysate from hypoxic mouse brain (lane 2) was resolved onto 10% SDS-PAGE and transferred onto NC Membrane, then immune-probed by Anti-HYOU1 antibody, at 1:500. An immunoreactive protein is observed around ~

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide next to the C-terminus of HYOU1 protein. This sequence is identical to rat, mouse, human and dog, bovine and horse origins.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: ~150 kDa
• Gene Name: hypoxia up-regulated 1
• Database Link:
  NP_001124463
  Entrez Gene 12282 MouseEntrez Gene 192235 RatEntrez Gene 10525 Human
  UniProt ID Q9Y4L1
• Background: The Hypoxia up-regulated 1 (HYOU1) protein belongs to the heat shock protein 70 family. It plays an important role in protein folding and secretion in the endoplasmic reticulum (ER). This protein is involved in stress-dependent induction, resulting in the accumulation of this protein in the ER under hypoxic conditions. It also has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness.
• Synonyms: GRP-170; Grp170; HSP12A; ORP-150; ORP150

Reference Data

• Protein Families: Transmembrane