CD20 (MS4A1) Mouse Monoclonal Antibody
Other products for "MS4A1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | A synthetic peptide corresponding to C-terminus of human CD20 protein. |
Formulation | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
Purification | The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 34 kDa |
Gene Name | membrane spanning 4-domains A1 |
Database Link | |
Background | CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on human pre B lymphocytes and B lymphocytes at all stages of maturation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and humanized CD20 antibodies has been reported in clinical study of lymphoma diseases. |
Synonyms | B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Hematopoietic cell lineage |
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