SOX2 Rabbit Polyclonal Antibody
Other products for "SOX2"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
| Reactivities | Bovine, Chicken, Human, Mouse, Rat, Canis |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide derived from N-terminus of Human SOX-2 protein. This sequence is identical among human, rat, mouse, bovine, chicken, and dog. |
| Formulation | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
| Purification | The Rabbit IgG is purified by Epitope Affinity Purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 35 kDa |
| Gene Name | SRY-box 2 |
| Database Link | |
| Background | The SOX2 is a transcription factor, a member of the SRY-related HMG-box (SOX) family involved in the regulation of embryonic development and in the determination of cell fate. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. When SOX-2 is expressed in self-renewing progenitor cells, it acts to inhibit neuronal differentiation. Sox-2 is considered as an appropriate cell-specific marker in vivo dynamics of the neural progenitor cell compartment as well as in the adult |
| Synonyms | ANOP3; MCOPS3 |
| Reference Data | |
| Protein Families | Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
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