Thymidine Kinase 1 (TK1) Rabbit Polyclonal Antibody

CAT#: TA354619

Rabbit anti TK1 (Thymidine Kinase) Polyclonal Antibody

Product Images

WB: The tissue extract derived from fruit fly was immunoblotted by Rabbit anti-TK1 at 1:500. An immunoreactive band is observed ~26 kDa.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Drosph
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to the N-terminus of fruit fly thymidine kinase protein.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: thymidine kinase 1
• Database Link:
  NP_003249
  Entrez Gene 7083 Human
  UniProt ID P04183
• Background: Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
• Synonyms: TK2

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism