BCL2L2 Rabbit Polyclonal Antibody

CAT#: TA354756

Rabbit anti BCL-w Polyclonal Antibody

Product Images

WB: The whole cell lysate derived from Hela cell was separated in 12% SDSPAGE, transferred onto NC membrane, and immunoblotted by Rabbit anti–Bcl-w antibody at 1:500. An immunoreactive band around ~21 kDa was observed.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Bovine, Chicken, Human, Mouse, Rat, Canis
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide derived from N-terminus of human BCL-W protein. This sequence is identical among human, rat and mouse origins.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21 kDa
• Gene Name: BCL2 like 2
• Database Link:
  NP_001186768
  Entrez Gene 12050 MouseEntrez Gene 60434 RatEntrez Gene 599 Human
  UniProt ID Q92843
• Background: BCL-w is a member of the Bcl-2 family. The gene codes for a 21 kDa protein which is essential for the regulation of cellular survival, and that is up-regulated in different human tumors, such as gastric and colorectal carcinomas. Inhibition of AKT activity may promote apoptosis through the down-regulation of Bcl-w protein and the consequential reduction in interaction of Bcl-w with pro-apoptotic members of the Bcl-2 family.
• Synonyms: BCL-W; BCL2-L-2; BCLW; PPP1R51

Reference Data

• Protein Families: Druggable Genome, Transmembrane