SOCS5 Rabbit Polyclonal Antibody

CAT#: TA354824

Rabbit anti SOCS-5 Polyclonal Antibody


USD 325.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 0.5-2 µg/ml FC Not tested
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to the C-terminus of SOCS-5 protein from human, mouse and rat origins.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 60 kDa
Gene Name suppressor of cytokine signaling 5
Background Cytokines induce a variety of biological responses by binding to specific cell surface receptors and activating cytoplasmic signal transduction pathways which are suppressed by other transcriptional factors. Proteins that mediate these signals from the cell surface to the nucleus include JAKs and STATs, while SOCS (Suppressor of cytokine signaling) proteins inhibit those signaling. The SOCS family comprises at least 8 members, SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). Structurally, the SOCS proteins are composed of an N terminal region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C terminal motif named the SOCS box. SOCS5 regulates IL-4 signaling through JAK1 negatively.
Synonyms CIS6; Cish5; CISH6; SOCS-5
Reference Data
Protein Families Druggable Genome
Protein Pathways Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.