Caveolin 1 (CAV1) Rabbit Polyclonal Antibody

CAT#: TA355003

Rabbit Polyclonal Anti-Caveolin-1 Antibody

Product Images

Western blot analysis of Caveolin-1 in human lung tissue lysate with Caveolin-1 antibody at (A) 1 and (B) 2ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-2µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Caveolin-1 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human Caveolin-1.
• Formulation: Caveolin-1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Caveolin-1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 20 kDa; Observed: 21 kDa
• Gene Name: caveolin 1
• Database Link:
  NP_001744
  Entrez Gene 12389 MouseEntrez Gene 25404 RatEntrez Gene 857 Human
  UniProt ID Q03135
• Background: Caveolin-1 Antibody: Caveolin-1 is a scaffolding protein that is the main component of the caveolae plasma membranes found in most cell types (1). The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression (2). The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade (3). Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy (4).
• Synonyms: BSCL3; CAV; CGL3; MSTP085; VIP21
• Note: Caveolin-1 antibody can be used for detection of Caveolin-1 by Western blot at 1 - 2 µg/ml.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Focal adhesion, Viral myocarditis