SRPK1 Rabbit Polyclonal Antibody
CAT#: TA355012
Rabbit Polyclonal Anti-SRPK1 Antibody
Other products for "SRPK1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1-2µg/mL.IHC: 5µg/ml. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | SRPK1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SRPK1. The immunogen is located within the first 50 amino acids of SRPK1. |
Formulation | SRPK1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | SRPK1 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 54, 72, 91 kDa; Observed: 91 kDa |
Gene Name | SRSF protein kinase 1 |
Database Link | |
Background | SRPK1 and SRPK2, two Arginine/serine-rich (SR) protein-specific kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells (1). They are highly specific for the phosphorylation of these RS proteins, and highly expressed in testis (1,2). SRPK1 plays a role in the condensation of sperm chromatin and controls the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis (3,4). |
Synonyms | SFRSK1 |
Note | SRPK1 antibody can be used for the detection of SRPK1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry at 5 µg/ml. |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Documents
Product Manuals |
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