SOX10 Rabbit Polyclonal Antibody

CAT#: TA355017

Rabbit Polyclonal Anti-SOX10 Antibody

Product Images

Western blot analysis of SOX10 in rat heart tissue lysate with SOX10 antibody at (A) 1 and (B) 2ug/ml.

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  Immunohistochemistry of SOX10 in rat heart tissue with SOX10 Antibody at 5ug/ml.

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  Immunofluorescence of SOX10 in rat heart tissue with SOX10 Antibody at 20ug/ml.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1-2µg/mL.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SOX10 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human SOX10.
• Formulation: SOX10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SOX10 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 51 kDa; Observed: 54 kDa
• Gene Name: SRY-box 10
• Database Link:
  NP_008872
  Entrez Gene 20665 MouseEntrez Gene 29361 RatEntrez Gene 6663 Human
  UniProt ID P56693
• Background: SOX10 Antibody: SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and the determination of the cell fate (1). The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins (2). This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development (2). Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschprung disease (3). SLC30A8 expression in beta-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).
• Synonyms: DOM; MGC15649; OTTHUMP00000195094; WS2E; WS4
• Note: SOX10 antibody can be used for Western blot at 1 - 2 µg/mL.

Reference Data

• Protein Families: Adult stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors