B7H3 (CD276) Mouse Monoclonal Antibody [Clone ID: 4H3]

CAT#: TA355140

Mouse Monoclonal Anti-B7-H3 Antibody [4H3]

USD 500.00

5 Days*

Size
    • 100 ug

Other products for "CD276"

Specifications

Product Data
Clone Name 4H3
Applications ELISA, FC, IF, IHC, WB
Recommended Dilution WB start at 0.25 ug/mL. IHC start at 2 ug/mL. ICC start at 1 ug/mL. IF start at 10 ug/mL. FC start at 1 ug/mL.
Reactivities Human
Host Mouse
Isotype IgG1, kappa
Clonality Monoclonal
Immunogen B7-H3 antibody was raised against the extracellular domain of human B7-H3
Formulation B7-H3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification B7-H3 Antibody is supplied as protein A purified IgG1.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 57 kDa; Observed: 100 kDa
Gene Name CD276 molecule
Background CD276, also known as B7-H3, was initially identified as a member of the B7 family of proteins through its homology with previously identified B7 molecules.CD276 mRNA is widely expressed, but its protein expression is usually rather low. CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response.In a similar fashion, CD276 plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity. It thus joins other immune checkpoint proteins as a possible therapeutic target for at least a subset of cancers.
Synonyms 4Ig-B7-H3; B7-H3; B7H3
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.