Androgen Receptor (AR) Mouse Monoclonal Antibody [Clone ID: AR27]
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Specifications
Product Data | |
Clone Name | AR27 |
Applications | IHC |
Recommended Dilution | 1:25 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Prokaryotic recombinant protein of 321 amino acids representing the N-terminus of the human androgen receptor |
Specificity | Human androgen receptor. |
Formulation | Liquid tissue culture supernatant containing sodium azide as a preservative |
Conjugation | Unconjugated |
Storage | Store at 2-8°C |
Stability | 12 months |
Gene Name | androgen receptor |
Database Link | |
Background | Androgen receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones (androgens). The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues e.g. prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors eg osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance. Furthermore, mutation of the gene encoding androgen receptor has been reported in prostatic carcinoma. |
Synonyms | AIS; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM |
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