CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: 5D11]

CAT#: TA355244

CD11c Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 5D11
• Applications: IHC
• Recommended Dilution: 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein containing 258 amino acids from the N-terminus of the external domain of the CD11c molecule
• Specificity: Human CD11c antigen
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: integrin subunit alpha X
• Database Link:
  Entrez Gene 3687 Human
• Background: CD11c is a member of the leukocyte integrin family of adhesion proteins. It is reported to be expressed in normal tissues, mainly on myeloid cells, for example, in bone marrow myelocytes, premyelocytes, metamyelocytes, non-segmented and segmented neutrophils with high levels reported on tissue macrophages and monocytes and with lowest levels in granulocytes. It is also reported to be expressed on NK cells, activated T cells, lymphoid cell lines, including hairy cell leukemias and a proportion of interdigitating dendritic cells.
• Synonyms: CD11C; SLEB6