CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: 2H7]

CAT#: TA355247

CD16 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 2H7
• Applications: IHC
• Recommended Dilution: 1:80
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the CD16 molecule, common to both the transmembrane form and the GPI-linked form
• Specificity: Human CD16 antigen
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: Fc fragment of IgG receptor IIIa
• Database Link:
  Entrez Gene 2214 Human
• Background: CD16 antigen has a molecular weight of 50 to 70 kD and is a low affinity Fc receptor for complexed IgG, Fc/gamma RIII, expressed on natural killer (NK) cells, granulocytes, activated macrophages and a subset of T cells expressing alpha-beta or gamma-delta T cell antigen receptors. The CD16 antigen exists both as a glycosyl-phosphatidylinositol (GPI)-anchored protein in polymorphonuclear cells and as a transmembrane protein in NK cells.
• Synonyms: CD16; CD16A; FCG3; FcgammaRIIIA; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3