CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: 2G9]

CAT#: TA355249

CD21 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 2G9
• Applications: IHC
• Recommended Dilution: 1:80
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the human CD21 molecule
• Specificity: Human CD21 molecule
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: complement component 3d receptor 2
• Database Link:
  Entrez Gene 1380 Human
• Background: CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.
• Synonyms: C3DR; CD21; SLEB9