CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: 10F11]

CAT#: TA355259

CD71 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 10F11
• Applications: IHC
• Recommended Dilution: 1:80
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71 molecule
• Specificity: Human CD71 molecule, also known as transferrin receptor
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: transferrin receptor
• Database Link:
  Entrez Gene 7037 Human
• Background: The CD71 molecule is a type II membrane glycoprotein with a molecular weight of approximately 180 kD. It is known as the transferrin receptor and is composed of two disulfide-bonded 90 kD subunits. The CD71 molecule plays a critical role in cell proliferation by controlling the supply of iron, an essential component for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. CD71 protein is reported to be expressed on activated B and T cells, macrophages, proliferating cells and metabolically active cells, for example, neurons.
• Synonyms: CD71; p90; T9; TfR; TfR1; TR; Trfr