Cytokeratin 20 (KRT20) Mouse Monoclonal Antibody [Clone ID: PW31]

CAT#: TA355266

CYTOKERATIN 20 Mouse Monoclonal Antibody


USD 1,090.00

3 Weeks*

Size
    • 1 ml

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Specifications

Product Data
Clone Name PW31
Applications IHC
Recommended Dilution 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Prokaryotic recombinant protein corresponding to a 70 amino acid component of the N-terminal region of the cytokeratin 20 intermediate filament protein.
Specificity Human cytokeratin 20 intermediate filament protein
Formulation Liquid tissue culture supernatant containing 15 mM sodium azide as a preservative
Conjugation Unconjugated
Storage Store at 2-8°C
Stability 12 months
Gene Name keratin 20
Background Cytokeratin 20 has been demonstrated to be almost entirely confined to the gastric and intestinal epithelium, urothelium and Merkel cells of the skin. Cytokeratin 20 is less acidic than other type I cytokeratins and is of interest due to its restricted tissue expression. In normal tissue, cytokeratin 20 is expressed in intestinal epithelium, gastric foveolar epithelium, a number of endocrine cells in the upper portions of the pyloric glands, urothelium and Merkel cells in epidermis. In tumors it is reported, there is a marked difference in the expression of cytokeratin 20 within different carcinomas. Neoplasms expressing cytokeratin 20 are derived from normal epithelia which themselves expressed cytokeratin 20. Colorectal carcinomas consistently express cytokeratin 20, while gastric adenocarcinomas express cytokeratin 20 to a lesser degree. Adenocarcinomas of the gall bladder and bile duct, ductal cell adenocarcinomas of the pancreas, mucinous ovarian tumors, Merkel cell tumors and transitional cell carcinomas have also been reported to express cytokeratin 20.
Synonyms CD20; CK-20; CK20; Cytokeratin-20; K20; Keratin-20; KRT21; MGC35423
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.