Cyclin D1 (CCND1) Mouse Monoclonal Antibody [Clone ID: P2D11F11]

CAT#: TA355280

CYCLIN D1 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: P2D11F11
• Applications: IHC
• Recommended Dilution: 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Prokaryotic fusion protein corresponding to the human cyclin D1 molecule
• Specificity: Human cyclin D1 protein
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: cyclin D1
• Database Link:
  Entrez Gene 595 Human
• Background: The D-type cyclins are a family of proteins which function primarily by regulating the activity of cyclin dependent kinases in the G1 phase of the cell cycle. Cyclin D1, a protein of 36 kD, is also known as PRAD1 or bcl-1. Maximum expression of cyclin D1 occurs at a critical point in mid to late G1 phase of the cell cycle. The cyclin D1 gene, located on 11q13 has been reported to be overexpressed in mantle cell lymphomas due to the chromosomal translocation t(11;18).
• Synonyms: BCL1; D11S287E; PRAD1; U21B31