TMEM16A (ANO1) Mouse Monoclonal Antibody [Clone ID: K9]

CAT#: TA355283

DOG-1 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: K9
• Applications: IHC
• Recommended Dilution: 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to part of the C-terminus of the cytoplasmic domain of the human DOG-1 molecule
• Specificity: Human DOG-1
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: anoctamin 1
• Database Link:
  Entrez Gene 55107 Human
• Background: DOG-1, a 986 amino acid protein of unknown function, is expressed predominantly on the plasma membrane of gastrointestinal stromal tumors (GISTs) and is rarely expressed in other soft tissue tumors, which, due to appearance, can be confused with GISTs. Reactivity for DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express KIT antigen.
• Synonyms: DOG1; FLJ10261; ORAOV2; TAOS2; TMEM16A