Ki67 (MKI67) Mouse Monoclonal Antibody [Clone ID: MM1]

CAT#: TA355308

Ki67 Antigen Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: MM1
• Applications: IHC
• Recommended Dilution: 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant fusion protein corresponding to a 1086 bp Ki67 motif-containing cDNA fragment.
• Specificity: Human Ki67 nuclear antigen expressed in all proliferating cells during late G1, S, M and G2 phases of the cell cycle
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: marker of proliferation Ki-67
• Database Link:
  Entrez Gene 4288 Human
• Background: The Ki67 antigen is a nuclear protein which is expressed in all active parts of the cell cycle (G1, S, G2 and mitosis) but is absent in resting cells (G0). In contrast to many other cell cycle-associated proteins, the Ki67 antigen is consistently absent in quiescent cells and is not detectable during DNA repair processes. Thus, the presence of Ki67 antigen is strictly associated with the cell cycle and confined to the nucleus, suggesting an important role in the maintenance and/or regulation of the cell division cycle.
• Synonyms: KI67; KIA