Laminin 2 alpha (LAMA2) Mouse Monoclonal Antibody [Clone ID: Mer3/22B2]
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Specifications
Product Data | |
Clone Name | Mer3/22B2 |
Applications | IHC |
Recommended Dilution | 1:50 - 1:100 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified protein from placenta |
Specificity | Reacts strongly with laminin alpha 2 chain of merosin in human and rabbit skeletal muscle. No reaction is observed in muscle sections from mouse, rat, dog, chicken, hamster or pig |
Formulation | Lyophilized tissue culture supernatant containing sodium azide as a preservative. |
Reconstitution Method | The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label |
Conjugation | Unconjugated |
Storage | Store at 2-8°C |
Stability | 12 months |
Gene Name | laminin subunit alpha 2 |
Database Link | |
Background | The muscle-specific form of laminin, merosin, is composed of three chains: alpha 2, beta 1 and gamma 1. Mutations in the chromosome 6 encoded gene for the laminin alpha 2 chain of merosin are responsible for a form of congenital muscular dystrophy (CMD). Merosin-negative CMD is characterized by a severe clinical phenotype and is associated with white matter changes on brain imaging. |
Synonyms | LAMM |
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