Laminin 2 alpha (LAMA2) Mouse Monoclonal Antibody [Clone ID: Mer3/22B2]

CAT#: TA355313

Merosin Laminin Alpha 2 Chain Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: Mer3/22B2
• Applications: IHC
• Recommended Dilution: 1:50 - 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified protein from placenta
• Specificity: Reacts strongly with laminin alpha 2 chain of merosin in human and rabbit skeletal muscle. No reaction is observed in muscle sections from mouse, rat, dog, chicken, hamster or pig
• Formulation: Lyophilized tissue culture supernatant containing sodium azide as a preservative.
• Reconstitution Method: The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: laminin subunit alpha 2
• Database Link:
  Entrez Gene 3908 Human
• Background: The muscle-specific form of laminin, merosin, is composed of three chains: alpha 2, beta 1 and gamma 1.
  Mutations in the chromosome 6 encoded gene for the laminin alpha 2 chain of merosin are responsible for a form of congenital muscular dystrophy (CMD). Merosin-negative CMD is characterized by a severe clinical phenotype and is associated with white matter changes on brain imaging.
• Synonyms: LAMM