Dihydropyrimidinase (DPYS) Mouse Monoclonal Antibody [Clone ID: 8D12]

CAT#: TA355378

DPYS Antibody

Specifications

Product Data

• Clone Name: 8D12
• Applications: WB
• Host: Mouse
• Clonality: Monoclonal
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 57
• Gene Name: dihydropyrimidinase
• Database Link:
  NP_001376
  Entrez Gene 1807 Human
  UniProt ID Q14117
• Background: Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
• Synonyms: DHP; DHPase; dihydropyrimidinase; hydantoinase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: beta-Alanine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Pantothenate and CoA biosynthesis, Pyrimidine metabolism