Dihydropyrimidinase (DPYS) Mouse Monoclonal Antibody [Clone ID: 8D12]
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Specifications
Product Data | |
Clone Name | 8D12 |
Applications | WB |
Host | Mouse |
Clonality | Monoclonal |
Specificity | Expected reactivity: Human |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 57 |
Gene Name | dihydropyrimidinase |
Database Link | |
Background | Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. |
Synonyms | DHP; DHPase; dihydropyrimidinase; hydantoinase |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | beta-Alanine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Pantothenate and CoA biosynthesis, Pyrimidine metabolism |
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