GCLM Mouse Monoclonal Antibody [Clone ID: 4B5]

CAT#: TA355383

GCLM Antibody

Product Images

WB Suggested Anti-GCLM Antibody Titration: 2.5 ug/ml Positive Control: THP-1 Whole Cell

Specifications

Product Data

• Clone Name: 4B5
• Applications: WB
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 30kDa
• Gene Name: glutamate-cysteine ligase modifier subunit
• Database Link:
  NP_002052
  Entrez Gene 2730 Human
  UniProt ID P48507
• Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
• Synonyms: GLCLR

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways