Ataxin 3 (ATXN3) Mouse Monoclonal Antibody [Clone ID: 4H6]

CAT#: TA355394

ATXN3 Antibody

Product Images

WB Suggested Anti-ATXN3 Antibody Titration: 5 ug/ml Positive Control: Hela Whole Cell

Specifications

Product Data

• Clone Name: 4H6
• Applications: WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 41
• Gene Name: ataxin 3
• Database Link:
  NP_001121168
  Entrez Gene 4287 Human
  UniProt ID P54252
• Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: AT3; ATX3; JOS; josephin; MJD; MJD1; SCA3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors