OAS1 Rabbit Polyclonal Antibody

CAT#: TA355451

OAS1 Antibody - C-terminal region

Product Images

WB Suggested Anti-OAS1 Antibody Titration: 1 ug/ml Positive Control: HepG2 cell lysate

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  Host: Rabbit Target Name: OAS1 Sample Type: Human Fetal Brain Antibody Dilution: 1.0ug/ml

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  Host: Rabbit Target Name: OAS1 Sample Type: Human MCF7 Antibody Dilution: 1.0ug/ml.OAS1 is strongly supported by BioGPS gene expression data to be expressed in MCF7

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  Host: Rabbit Target Name: OAS1 Sample Type: Human 293T Antibody Dilution: 1.0ug/mlOAS1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells

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  Host: Rabbit Target: OAS1 Positive control (+): Human Stomach Tumor (T-ST) Negative control (-): 293T Cell Lysate (2T) Antibody concentration: 3ug/ml

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  Immunohistochemistry with Small intestine tissue at an antibody concentration of 5ug/ml using anti-OAS1 antibody (TA355451)

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Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 46kDa
• Gene Name: 2'-5'-oligoadenylate synthetase 1
• Database Link:
  NP_058132
  Entrez Gene 4938 Human
  UniProt ID P00973
• Background: OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.
• Synonyms: E18/E16; IFI-4; OIAS; OIASI

Reference Data

• Protein Families: Druggable Genome