ASCL1 Rabbit Polyclonal Antibody

CAT#: TA355477

ASCL1 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: ASCL1 Sample Type: RPMI-8226 Whole Cell lysates Antibody Dilution: 1.0ug/ml

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  Host: Mouse Target Name: ASCL1 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ASCL1
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 25kDa
• Gene Name: achaete-scute family bHLH transcription factor 1
• Database Link:
  NP_004307
  Entrez Gene 429 Human
  UniProt ID P50553
• Background: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
• Synonyms: ASH1; bHLHa46; HASH1; MASH1