P2RX7 Rabbit Polyclonal Antibody

CAT#: TA355776

P2RX7 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: P2RX7 Sample Tissue: Human Hela Antibody Dilution: 1.0ug/ml

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  Host: Rabbit Target: P2RX7 Positive control (+): THP-1 (N30) Negative control (-): A549 (N03) Antibody concentration: 1ug/ml

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  Human kidney

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX7
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Cow: 93%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 69kDa
• Gene Name: purinergic receptor P2X 7
• Database Link:
  Entrez Gene 5027 Human
  UniProt ID Q99572
• Background: The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
• Synonyms: MGC20089; P2X7