Kl Rabbit Polyclonal Antibody

CAT#: TA355850

Kl Antibody - N-terminal region

Product Images

WB Suggested Anti-Kl Antibody Titration: 1.0 ug/ml Positive Control: Mouse Small Intestine

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 91%; Rabbit: 92%; Rat: 92%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 116kDa
• Gene Name: klotho
• Database Link:
  NP_038851
  Entrez Gene 16591 Mouse
  UniProt ID O35082
• Background: Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.
• Synonyms: klotho