c Rel (REL) Rabbit Polyclonal Antibody

CAT#: TA355861

REL Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: Rel Sample Type: Mouse Kidney lysates Antibody Dilution: 1.0ug/ml

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  Host: Mouse Target Name: REL Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of mouse REL
• Specificity: Expected reactivity: Mouse
  Homology: Mouse: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 64kDa
• Gene Name: REL proto-oncogene, NF-kB subunit
• Database Link:
  NP_001278675.1
  UniProt ID Q04864
• Background: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: C-Rel; I-Rel