Gria1 Rabbit Polyclonal Antibody

CAT#: TA355900

Gria1 Antibody - N-terminal region

Product Images

WB Suggested Anti-Gria1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 102kDa
• Gene Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
• Database Link:
  NP_001106796
  Entrez Gene 14799 Mouse
  UniProt ID P23818
• Background: Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
• Synonyms: GluA1; GLUH1; GluR-A; gluR-A; GLUR1; GLURA; GluRA; HBGR1; HIPA1