Klhl12 Rabbit Polyclonal Antibody

CAT#: TA356038

Klhl12 Antibody - N-terminal region

Product Images

WB Suggested Anti-Klhl12 Antibody Titration: 1.0 ug/ml Positive Control: Rat Brain

Specifications

Product Data

• Applications: WB
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 62kDa
• Gene Name: kelch-like family member 12
• Database Link:
  NP_714952
  Entrez Gene 266772 Rat
  UniProt ID Q8R2H4
• Background: Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
• Synonyms: C3IP1; DKIR; FLJ27152