SALL3 Rabbit Polyclonal Antibody

CAT#: TA356069

SALL3 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: SALL3 Sample Tissue: Human A549 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SALL3
• Specificity: Expected reactivity: Human
  Homology: Cow: 79%; Dog: 79%; Human: 100%; Mouse: 100%; Pig: 85%; Rat: 100%; Zebrafish: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 143 kDa
• Gene Name: spalt like transcription factor 3
• Database Link:
  NP_741996
  UniProt ID Q9BXA9
• Background: This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
• Synonyms: hSALL3; ZNF796