Granzyme K (GZMK) Rabbit Polyclonal Antibody

CAT#: TA356471

GZMK Antibody - N-terminal region

Product Images

WB Suggested Anti-GZMK Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK
• Specificity: Expected reactivity: Horse, Human, Pig
  Homology: Horse: 79%; Human: 100%; Pig: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 26kDa
• Gene Name: granzyme K
• Database Link:
  NP_002095
  Entrez Gene 3003 Human
  UniProt ID P49863
• Background: GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
• Synonyms: Fragmentin-3; Granzyme-3; NK-TRYP-2; NK-tryptase-2; PRSS; TRYP2

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane