PTPRN Rabbit Polyclonal Antibody

CAT#: TA356513

PTPRN Antibody - middle region

Product Images

Host: Rabbit Target Name: PTPRN Sample Tissue: Human Liver Tumor Antibody Dilution: 1ug/ml

• 

  Host: Rabbit Target Name: PTPRN Sample Type: Human Kidney Antibody Dilution: 0.5 ug/ml

• 

  Host: Rabbit Target Name: PTPRN Sample Tissue: Human A172 Whole Cell Antibody Dilution: 5ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PTPRN
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 86%; Dog: 100%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 96kDa
• Gene Name: protein tyrosine phosphatase, receptor type N
• Database Link:
  NP_001186692
  Entrez Gene 5798 Human
  UniProt ID Q16849
• Background: PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
• Synonyms: FLJ16131; IA-2; IA-2/PTP; IA2; ICA3; ICA512; R-PTP-N

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Type I diabetes mellitus