Rora Rabbit Polyclonal Antibody

CAT#: TA356565

Rora Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: Rora Sample Type: Mouse Lung lysates Antibody Dilution: 1.0ug/ml

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  Host: Rabbit Target Name: RORA Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml

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  Host: Mouse Target Name: RORA Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rora
• Specificity: Expected reactivity: Cow, Human, Mouse, Rat
  Homology: Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 59kDa
• Gene Name: RAR-related orphan receptor alpha
• Database Link:
  NP_038674
  Entrez Gene 19883 Mouse
  UniProt ID P51448
• Background: Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives.
• Synonyms: DKFZp686M2414; MGC119326; MGC119329; NR1F1; ROR-alpha; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA